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ADAMTS-13 regulates VWF function by cleaving it at the central A2 domain, thereby reducing its prothrombogenic potential and repressing thrombosis-induced inflammation through downregulation of P-selectin (17, 80, 81)

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It binds to these substances and transforms them into water-soluble forms that can be excreted through urine or bile

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Talib W.H., Mahmod A.I., Kamal A., Rashid H.M., Alashqar A.M.D., Khater S., Jamal D., Waly M

[1] (Note: emerging international terminology uses MASLDmetabolic dysfunction-associated steatotic liver diseasethough NAFLD remains the term used in current NICE and NHS guidance.) Glutathione is a naturally occurring tripeptide composed of three amino acids: cysteine, glutamic acid, and glycine